Spravato (Esketamine) is an innovative treatment for individuals living with treatment-resistant depression (TRD).
At Bethel Psychiatry, a specialized Spravato clinic, we understand that preparation is key to getting the most benefit from your Spravato appointment.
Bringing the right items and knowing what to expect can make your experience more comfortable, focused, and effective.
Below, we will help you understand what to bring and how to prepare for your Spravato appointment so you can get the most benefit from each session.

What Is Spravato Therapy?

Spravato is a nasal spray that is prescribed by doctors. It’s meant for people with treatment-resistant depression. You must use it under medical supervision. It works differently from other antidepressants. Some patients may feel relief faster.

The specific steps in Spravato treatment typically include:

  1. Initial assessment
  2. Medical history review
  3. Nasal spray administration in the clinic
  4. Two hours of observation
  5. Follow-up appointments

Each step is designed to ensure your safety, comfort, and progress.
At Bethel Psychiatry, our clinicians will help you learn how to take Spravato on your first visit.

What Should You Bring to Your Spravato Appointment?

Personal Identification and Medical Information

Bring a valid photo ID and a current list of medications:

Spravato may interact with some drugs, so this information helps your clinician to deliver safe and effective care. Bringing the contact of your primary care doctor also helps.

Comfortable Clothing

Each appointment lasts about two hours, so comfort is important. We recommend:

  • Loose, comfortable clothing
  • A sweater or hoodie in case the room feels cool
  • Slip-on shoes
  • Comfortable pants or leggings

Feeling physically relaxed can make your experience much smoother.

Food and Beverage Considerations

Before your visit:

  • Eat a light meal
  • Drink water
  • Avoid soda, coffee and energy drinks
  • Do not drink alcohol at least 24 hours beforehand

Transportation Arrangements

After your Spravato session, you may experience dizziness, sedation or temporary changes in perception. For this reason, it is required that patients arrange for:

  • A trusted adult to drive you home
  • Your driver’s contact information
  • Clear pickup timing

Your safety is our top priority.

Mental Preparation Tools

Spravato is most effective when one is psychologically prepared and in a state of calmness. Carry things that could make you feel relaxed and clear-headed, including:

  • Music and relaxing headphones
  • A journal or notebook to track thoughts or feelings before and after treatment
  • Comfort objects like a small pillow or blanket

Many patients find that establishing intentions or goals of the session increases the overall therapeutic effect.

Electronic Devices

It is helpful to bring a smartphone or tablet for:

  • Listening to music
  • Sending a message to your driver

Try not to use it too much so you can relax.

Relaxation and Coping Techniques

Spravato might lead to brief detachment or dizziness. Planning with stress management strategies alleviates worry and improves your experience. Bring:

  • Breathing exercises guide or app
  • Mindfulness or meditation materials
  • A calm, quiet mindset

Practicing these techniques before your session improves comfort and allows the medication to work effectively.

The Most Important Thing to Bring: A Supportive Mindset

Healing is a process. Come with:

  • Openness to the experience
  • Willingness to communicate with your care team
  • Patience with yourself

You are not detached in this journey.

Tips for a Better Visit

  • Write down questions for your provider
  • Plan to rest for the remainder of the day
  • Track how you feel after each session in a notebook

This helps you and your care team monitor progress.

A Gentle Note from Bethel Psychiatry

At Bethel Psychiatry, we want you to feel safe, supported and understood. Our team will guide you through every step of the Spravato process. We monitor you closely, respond to your queries and attend to you with care during your visit.
If you are concerned about the cost of treatment, we can inform you about Spravato patient assistance programs and prepare you for your appointment. Just contact us.

FAQs

What is a typical Spravato schedule?

A standard Spravato therapy begins with twice-weekly therapy sessions and then changes to once a week or twice per week sessions according to your response to the medication.

Is Spravato effective?

Spravato improves treatment-resistant depression in many patients and can be used alongside therapy and continuous psychiatric care. Things may turn out to be different, yet there is hope.